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Vecuronium

Vecuronium bromide
(Norcuron®)

CLASS

Nondepolarizing neuromuscular blocker

DOSAGE

    Adult & Pediatric (over 16 years of age): 0.1 mg/kg slow administration (30-60 seconds) IV.

    Usually 5-7 mg for an average sized adult.

    ACTIONS

      Vecuronium bromide is a non-depoarizing skeletal muscle relaxant. Binding with cholinergic receptor sites inhibits transmission of nerve impulses, antagonizing the action of acetylcholine. Has no analgesic properties and the patient maybe conscious, but unable to communicate by any means. First muscles affected include eyes, face, neck; followed by limbs, abdomen, chest; diaphragm affected last. Recovery usually occurs in the reverse order and may take longer than 60 minutes. IV onset of actions in 30-60 seconds, peaks in 3-5 minutes and lasts for 30-60 minutes.

    INDICATIONS

      Authorized paramedic only may induce general anesthesia to facilitate intubation. It may also be used by a paramedic post intubation during treatment of the patient.

    CONTRAINDICATIONS

    WARNINGS

      Causes respiratory paralysis; supportive airway control must be continuous and under direct observation at all times. Myasthenia gravis and other neuromuscular diseases increase sensitivity to the drug.

    SIDE EFFECTS

      Hypersensitivity reactions are possible.

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