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Lidocaine Hydrochloride


Antiarrhythmic agent, Antidysrhythmic (class Ib)
Local anesthetic, Topical

ET purpose: 1.5 mg/kg for onset within 45 - 90 seconds

IO purpose: inject 1% Lidocaine into s.q. area of IO insertion site. Enough Lidocaine should be given to make slight skin bleb prior to IO insertion

To be used during intubation of patients with posiible ICP or reactive airway disease.

Used to assist in the implemntation of the easy IO.

- Allergy to caine related anesthetics
- Severe heart block
- Bradycardia unless pacemaker is in place
- WPW (Wolff-Parkinson-White syndrome)
- Pregnancy
- Use with caution in hypovolemic and cardiogenic shock


Pregnancy safety: Category B.

Possible medication interactions that may occur:

- Metabolic clearance of lidocaine may be decreased in patients taking beta-adrenergic blockers or in patients with liver dysfunction.
- Apnea induced with succinylcholine may be prolonged with large doses of lidocaine.
- Cardiac depression may occur if lidocaine is given concomitantly with IV phenytoin.
- Additive neurological effects may occur with procainamide.


Administration of Lidocaine may cause lightheadedness, confusion, blurred vision, hypotension, cardiovascular collapse, bradycardia, CNS depression (altered level of consciousness, slurred speech, irritability, muscle twitching, seizures) with high doses
and localized anesthetic effects.

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