Haldol

Haloperidol
(Haldol®)

CLASS

Antipsychotic agent, Major tranquilizer

DOSAGE

Adult: 5-10 mg IM/IN.
Follow with 50mg of Benadryl IM

ACTIONS

Haloperidol is a potent, long-acting Butyrophenone derivative with pharmacologic actions similar to those of Piperazine Phenothiazines but with higher incidence of extrapyramidal effects, less hypotensive and relatively low sedative activity. Exerts strong anti-emetic effect, and impairs central thermoregulation. Produces weak central anti-cholinergic effects and transient orthostatic hypotension. Actions thought to be due to blockade of Dopamine activity.

INDICATIONS

Used for management of manifestations of psychotic disorders and for the treatment of agitated states in acute and chronic psychoses.

CONTRAINDICATIONS

Combativeness from trauma, Hypersensitivity to Haloperidol, Parkinson's disease, seizure disorders, coma, alcoholism, severe mental depression, CNS depression, Thyrotoxicosis, and cocaine overdose.

Should not be administered in the presence of other sedatives. Should not be used in the management of dysphoria caused by Talwin

WARNINGS

Orthostatic hypotension

Use with caution in patients: with severe cardiovascular disorders (may cause transient hypotension and/or precipitation of anginal pain), receiving anticonvulsant medication (may lower the convulsive threshold), with a history of allergic reactions to drugs.

SIDE EFFECTS

CNS:Parkinson like symptoms, restlessness, lethargy, headache, exacerbation of psychotic symptoms.

Cardio:Tachycardia, hypotension, hypertension (with overdose).

GI:Nausea, vomiting.

Other:Bronchospasm, laryngospasm, respiratory depression, dry mouth, hyper-salivation,drooling.